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. 2022 Oct 20;13(12):1575–1586. doi: 10.1039/d2md00246a

Data collection and refinement statistics of the dataset of T-p53C-Y220C soaked with compound 1151 (PDB: 8A92). Values in parentheses indicate the respective value of the highest resolution bin.

Compound 1151 (PDB: 8A92)
Wavelength [Å] 0.92
Space group P212121
Cell dimensions
a, b, c [Å] 65.1, 74.1, 105.2
α, β, γ [°] 90, 90, 90
Resolution range [Å] 50–1.37 (1.45–1.37)
Redundancy 13.2 (13.3)
Completeness [%] 100 (100)
Mean I/σ(I) 14.4 (1.0)
R-meas [%] 11.7 (256.8)
CC1/2 [%] 99.9 (49.7)
Wilson B2] 22.8
Resolution included [Å] 43.68–1.37
R work/Rfree [%] 15.32/18.32
Bond RMSD [Å] 0.008
Angle RMSD [°] 0.99
Ramachandran [%] (favored/allowed/outliers) 98.98/1.02/0
Rotamer outliers [%] 1.43
All-atom Clashscore 1.44
Average B factor [Å2]
Overall 22.34
Protein 20.03
Ligand 41.4
Water 35.58