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. 2022 Nov 14;10(1):e200052. doi: 10.1212/NXI.0000000000200052

Figure 1. Schematic Diagram of the Study Inclusion Criteria.

Figure 1

Patients were classified as progressive MS based on the presence of a confirmed EDSS score ≥3 at least 3 months apart and included in the study. The first visit at or after a confirmed EDSS score ≥3 with available serum sample within 6 months was retained as the baseline visit and as the baseline serum sample, respectively. Patients who experienced a 6mCDP after baseline were classified as progressors. 6mCDP = 6-month confirmed disability progression; EDSS = Expanded Disability Status Scale; MS = multiple sclerosis; PMS = progressive MS.