Summary of biological activities of test compounds.

Compound	Structure	Clog Pa	M. bovis BCG
			MIC50b	MIC90b
3		7.17	4.0 (4.0, 4.0)	5.6 (5.8, 5.5)
4		8.05	2.4 (2.6, 2.2)	4.6 (4.6, 4.6)
5		9.10	1.2 (1.2, 1.2)	2.3 (2.4, 2.2)
6		10.16	0.59 (0.6, 0.58)	1 (1, 1)
7		11.22	0.5 (0.6, 0.5)	0.8 (0.9, 0.7)
8		9.31	5.5 (6.7, 4.4)	10.5 (10.2, 10.8)
9		11.42	2.1 (2, 2.2)	2.8 (2.7, 2.8)
10		9.66	3.8 (3.8, 3.8)	5.6 (5.7, 5.6)
11		11.78	0.9 (0.9, 1.0)	1.4 (1.4, 1.4)
12		9.53	1 (1.05, 1)	1.4 (1.4, 1.4)
13		11.65	3.8 (3.6, 4.05)	5.7 (5.5, 5.9)
14		11.83	1.8 (1.7, 1.9)	2.8 (2.7, 2.8)
15		9.72	0.65 (0.6, 0.7)	1.2 (1.2, 1.3)
16		−1.23	28.7 (32.5, 25.0)	48.5 (48.0, 49.0)
17		4.91	1.3 (1.3, 1.3)	2.5 (2.6, 2.5)
18		7.02	0.6 (0.6, 0.6)	0.9 (1.0, 0.8)
19		11.81	0.7 (0.7, 0.7)	1.4 (1.4, 1.4)

^aClog P values were estimated using ChemDraw Professional 16.0.

^bMinimum inhibitory concentration (in μM) required to reduce growth by 50% (MIC₅₀) or 90% (MIC₉₀) compared to untreated controls.