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. 2022 Oct 13;13(12):1605–1613. doi: 10.1039/d2md00251e

Cytotoxicity evaluation of 6, 7, and 18. IC50, concentration required to reduce growth of Vero E6 (African green monkey kidney epithelial cells) by 50% compared to untreated controls, are averages of three separate determinations.

6 7 18
Vero E6 IC50 (μM) 12.4 (± 0.1) 5.6 (± 0.2) 4.1 (± 0.3)
SI (IC50 Vero/MIC50 M. bovis BCG) 21 11 7