Cytotoxicity evaluation of 6, 7, and 18. IC50, concentration required to reduce growth of Vero E6 (African green monkey kidney epithelial cells) by 50% compared to untreated controls, are averages of three separate determinations.
| 6 | 7 | 18 | |
|---|---|---|---|
| Vero E6 IC50 (μM) | 12.4 (± 0.1) | 5.6 (± 0.2) | 4.1 (± 0.3) |
| SI (IC50 Vero/MIC50 M. bovis BCG) | 21 | 11 | 7 |