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. 2022 Dec 14;8(50):eadd1436. doi: 10.1126/sciadv.add1436

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Fig. 5. — (A) Initial and final tube radii after the accumulation of ATG12–ATG5-ATG16L1 onto the membrane tube. Vectors color-coded for slope of the change in protein density over the change in tube radius, where darker colors indicate a steeper negative slope. (B) Montage of a single representative membrane tube showing ATG12–ATG5-ATG16L1 localization relative to the tube and membrane tube intensity over time. Snapshots of a continuous acquisition every 6 s, showing ATG16L1-GFP (green) and ATTO647N-DOPE membrane (magenta). Scale bars, 10 μm. (C) Quantification of protein binding and membrane tube radius from time course in (B). Surface density of ATG16L1 dimers on the membrane tube (cyan) and membrane tube radius (magenta) plotted against time (s) for an 80-s time course.