FIG. 3.

(A and B) Immunohistochemical staining of murine lungs for MIP-2 antigen 3 h after intratracheal instillation of LPS in control (A) and diabetic (B) mice. (C) Control section incubated with control serum. The arrows point to AMs. Note that AMs immunoreactive with MIP-2 are present only within the lungs of control mice. The lung of the diabetic mouse showed no AMs staining for MIP-2. Staining for MIP-2 was specific, since no staining was present in sections of the lung incubated with purified IgG from control serum. Magnification, ×200. The conditions of LPS administration are the same as in Fig. 1.