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. 2022 Dec 9;101(49):e31799. doi: 10.1097/MD.0000000000031799

Table 2.

Summary pooled HR (95% CI) for subgroup analyses of OS, PFS and CSS using random-effects models.

Cancer site OS P value PFS P value CSS P value
HR 95% CI HR 95% CI HR 95% CI
breast 0.77 0.69–0.86 .000 0.64 0.44–0.91 .013 0.84 0.73–0.96 .009
colorectal 0.81 0.65–1.01 .060 1.00 0.89–1.13 .998 0.77 0.64–0.94 .008
endometrial 0.65 0.44–0.97 .034 0.73 0.37–1.45 .371
head and neck 0.92 0.77–1.09 .308 0.77 0.41–1.44 .415
hepatocellular 0.75 0.58–0.97 .027
lung 0.79 0.69–0.92 .002 0.61 0.48–0.79 .000
ovarian 0.61 0.32–1.16 .131 0.37 0.25–0.55 .000
pancreatic 0.80 0.67–0.95 .011
prostate 0.94 0.87–1.02 .141 1.01 0.80–1.28 .941 0.83 0.70–0.98 .030
overall 0.81 0.77–0.85 .000 0.76 0.66–0.87 .000 0.79 0.73–0.86 .001

95%CI = 95% confidence interval, CSS = cancer-specific survival, HR = hazard ratio, OS = overall survival, PFS = progression-free survival.