Table 4.
Summary of newly calculated MCIDs reported in TKA, separated by calculation method
| Anchor-based | Distribution-based | Combined | |||||
| PROM | Median | IQR (Q1 to Q3) | Median | IQR (Q1 to Q3) | Median | IQR (Q1 to Q3) | p valuea |
| OKS | 6 | 4 to 7 | 7 | 5 to 10 | 6 | 5 to 9 | 0.29 |
| WOMAC | 15 | 10 to 23 | 10 | 10 to 11 | 12 | 10 to 17 | 0.20 |
| Function | 23 | 16 to 33 | 11 | 10.8 to 11 | 20 | 15 to 33 | 0.04 |
| Pain | 25 | 14 to 31 | 22 | 17 to 23 | 23 | 13 to 29 | 0.33 |
| Stiffness | 13 | 11 to 14 | 28 | 28 to 29 | 15 | 12 to 28 | 0.20 |
| KSS | |||||||
| Function | 7 | 6 to 10 | 6 | 6 | 6 | 6 to 9 | 1.0 |
| Knee | 6 | 5 to 8 | 7 | 7 | 7 | 5 to 7 | 1.0 |
| KOOS | 87 | 85 to 90 | 35 | 23 to 42 | 49 | 35 to 83 | 0.20 |
| Pain | 22 | 20 to 23 | 10 | 9 to 11 | 12 | 10 to 20 | 0.01 |
| QoL | 17 | 13 to 15 | 12 | 8 to 13 | 13 | 11 to 13 | 0.37 |
| ADL | 18 | 14 to 23 | 10 | 9 to 11 | 12 | 10 to 14 | 0.01 |
| Symptoms | 11 | 9 to 13 | 11 | 10 to 12 | 11 | 10 to 12 | 0.90 |
| Sports/recreation | 18 | 18 | 16 | 13 to 16 | 16 | 16 to 18 | 0.14 |
| KOOS JR | 14 | 7 to 18 | 8 | 7 to 9 | 9 | 7 to 12 | 0.25 |
| KOOS-12 | 20 | 18 to 21 | NR | NR | 20 | 18 to 21 | n/a |
| Function | 20 | 19 to 21 | NR | NR | 20 | 19 to 21 | n/a |
| Pain | 17 | 15 to 19 | NR | NR | 17 | 15 to 19 | n/a |
| QoL | 22 | 18 to 23 | NR | NR | 22 | 18 to 23 | n/a |
| SF-12 PCS | 3 | 2 to 4 | 5 | 5 to 7 | 5 | 3 to 5 | 0.10 |
| SF-12 MCS | 0.1 | -0.7 to 0.8 | 5 | 5 to 10 | 5 | 2 to 5 | 0.20 |
| SF-36 composite | 10 | 10 | NR | NR | 10 | 10 | n/a |
| SF-36 PCS | NR | NR | 10 | 10 | 10 | 10 | n/a |
| VAS-D, mm | 23 | 23 | 16 | 16 | 19 | 18 to 21 | n/a |
| NRS Walking | 1 | 1 | NR | NR | 1 | 1 | n/a |
| PROMIS-GH PCS | 3 | 2.9 to 3.4 | 2.3 | 2.3 | 2.5 | 2.3 to 3.4 | 0.12 |
| PROMIS-GH MCS | 4 | 3.0 to 4.3 | NR | NR | 4 | 3.0 to 4.3 | n/a |
| FJS | 13 | 11 to 14 | 12 | 12 | 13 | 11 to 14 | 1.0 |
| EQ-5D-3L | 0.07 | 0.06 to 0.08 | 0.29 | 0.24 to 0.62 | 0.14 | 0.07 to 0.26 | 0.10 |
| UCLA | NR | NR | 0.9 | 0.9 | 0.9 | 0.9 | n/a |
| HSS | 5 | 5 | NR | NR | 5 | 5.4 | n/a |
Wilcoxon rank sum nonparametric test comparison of anchor-based and distribution-based medians with assumption of non-normal distribution. MCID = minimum clinically important difference; NR = not reported; IQR = interquartile range; Q1 = quartile 1; Q3 = quartile 3; n/a = not applicable secondary to insufficient data for comparison; OKS = Oxford Knee Score; KSS = Knee Society Score; KOOS = Knee Injury and Osteoarthritis Outcome Score; PF = physical functioning; RP = role limitations because of physical health; BP = bodily pain; GH = general health; MCS = Mental Component Summary; VT = vitality; SF = social functioning; RE = role limitations because of emotional problems; MH = mental health; NRS = Numeric Rating Scale; PROMIS-GH PCS = Patient-Reported Outcomes Measurement Information System Global Health Physical Component Summary; FJS= Forgotten Joint Score; EQ-5D = EuroQal 5-Dimensions; VR-12 PCS = Veteran Rands 12-Item Health Survey Physical Component Summary; VR-12 MCS = Veteran Rands 12-Item Health Survey Mental Component Summary; UCLA = University of California Los Angeles Score.