Table 2.
Mice | ||||||||
---|---|---|---|---|---|---|---|---|
Marker | KC1 | KC2 | MoMFs | Monocytes | LCMs | cDC1 | cDC2 | pDCs |
CD11b | low | low | high | high | + | – | + | + |
CD11c | – | – | – | – | low | + | + | – |
CD68 | + | + | – | – | – | – | – | – |
F4/80 | high | high | int | – | low | – | – | – |
Clec4F | + | + | – | – | – | – | – | – |
Tim4 | + | + | – | – | – | – | – | – |
MARCO | + | + | – | – | – | – | – | – |
CD5L | + | + | – | – | – | – | – | – |
VSIG4 | + | + | – | – | – | – | – | – |
Ly6C | – | – | high/int | high | – | – | + | – |
CSFR1 | + | + | + | + | + | – | – | – |
CD206 | low | high | – | – | – | – | – | – |
ESAM | – | + | – | – | – | – | – | – |
CD103 | – | – | – | – | – | +/- | – | – |
CD8α | – | – | – | – | – | +/- | – | – |
CX3CR1 | – | – | – | – | high | – | + | – |
XCR1 | – | – | – | – | – | + | – | – |
MHC II | – | – | – | – | + | + | – | – |
Siglec-H | – | – | – | – | – | – | – | + |
CD317 | – | – | – | – | – | – | – | + |
Human | ||||||||
Marker | Pro-inflammatory KCs | Anti-inflammatory KCs | Intermediate Monocytes | Classical Monocytes | Non-classical Monocytes | pDCs | cDC1 | cDC2 |
CD11b | + | + | + | + | + | + | – | + |
CD11c | – | – | – | – | – | – | + | + |
CD68 | + | + | – | – | – | – | – | – |
TIMD4 | + | + | – | – | – | – | – | – |
MARCO | – | + | – | – | – | – | – | – |
CD5L | + | + | – | – | – | – | – | – |
VSIG4 | – | + | – | – | – | – | – | – |
CD163 | – | + | – | – | – | – | – | – |
HMOX1 | – | + | – | – | – | – | – | – |
CD14 | – | – | + | high | – | – | – | – |
CD16 | – | – | + | – | high | – | – | – |
CCR2 | – | – | +/- | – | – | – | – | – |
HLA-DR | – | – | – | – | – | + | + | + |
CD123 | – | – | – | – | – | + | – | – |
XCR1 | – | – | – | – | – | – | + | – |
CLEC9A | – | – | – | – | – | – | + | – |
CD1c | – | – | – | – | – | – | – | + |
SIRPα | – | – | – | – | – | – | – | + |
CD172a | – | – | – | – | – | – | – | + |
CD303 | – | – | – | – | – | + | – | – |
CD85g | – | – | – | – | – | + | – | – |
KCs, Kupffer Cells; MoMFs, Monocyte-Derived Macrophages; LCM, Liver Capsular Macrophages; cDCs, Conventional Dendritic Cells; pDCs, Plasmocytoid Dendritic Cells; +, positive; -, negative; int, intermediate.