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. 2022 Nov 30;13:1029085. doi: 10.3389/fimmu.2022.1029085

Table 2.

Basic markers of hepatic mononuclear phagocytes in mice and humans (55, 6672).

Mice
Marker KC1 KC2 MoMFs Monocytes LCMs cDC1 cDC2 pDCs
CD11b low low high high + + +
CD11c low + +
CD68 + +
F4/80 high high int low
Clec4F + +
Tim4 + +
MARCO + +
CD5L + +
VSIG4 + +
Ly6C high/int high +
CSFR1 + + + + +
CD206 low high
ESAM +
CD103 +/-
CD8α +/-
CX3CR1 high +
XCR1 +
MHC II + +
Siglec-H +
CD317 +
Human
Marker Pro-inflammatory KCs Anti-inflammatory KCs Intermediate Monocytes Classical Monocytes Non-classical Monocytes pDCs cDC1 cDC2
CD11b + + + + + + +
CD11c + +
CD68 + +
TIMD4 + +
MARCO +
CD5L + +
VSIG4 +
CD163 +
HMOX1 +
CD14 + high
CD16 + high
CCR2 +/-
HLA-DR + + +
CD123 +
XCR1 +
CLEC9A +
CD1c +
SIRPα +
CD172a +
CD303 +
CD85g +

KCs, Kupffer Cells; MoMFs, Monocyte-Derived Macrophages; LCM, Liver Capsular Macrophages; cDCs, Conventional Dendritic Cells; pDCs, Plasmocytoid Dendritic Cells; +, positive; -, negative; int, intermediate.