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. 2022 Dec 14;9(4):277–286. doi: 10.1055/s-0042-1758204

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The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. ( https://creativecommons.org/licenses/by/4.0/ )

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 2 — Box-Whisker plots demonstrating (a) the gene expression profile of hsa-mir-421 ( p value = 1.11 × 10-16) in HNSC dataset, (b) the expression profile of hsa-mir-421 based on mutation status (Normal vs TP53 mutant - p value = 1.62 × 10-12; TP53 mutant Vs TP53 non-mutant - p value = 1.15 × 10-4), (c) Kaplan-Meier survival plot showing significant difference in survival rate upon change in expression levels of hsa-mir-548f-1 ( p value = 0.018). A p value less than 0.05 is considered to be significant.