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. 2022 Jul 22;29(12):1918–1929. doi: 10.1038/s41417-022-00507-9

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A Oesophageal, gastric, duodenal and pancreas fibroblasts were infected with the indicated OVs at MOI 10 after which cell viability was determined 5 days post-infection. B GI fibroblast cell viability is shown according to the expression of JAM-A as determined by flow cytometry (++: MFI > 1500, +: MFI 500–1500, +/−: MFI 250-500, −: MFI < 250). C Pearson’s correlation of JAM-A MFI and cell viability as assessed by flow cytometry and WST-1 assay. Left panel shows correlation for R124 (R = −0.5775, p = 0.0003) and right panel for jin-3 (R = −0.5248, p = 0.0014). MFI = mean fluorescence intensity, C = CAF, N = tumor-adjacent.