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. 2022 Jul 22;29(12):1918–1929. doi: 10.1038/s41417-022-00507-9

Fig. 3. Overexpression and ablation of JAM-A in pancreatic fibroblasts.

Fig. 3

A JAM-A expression on hPS1 pancreatic stellate cells transduced with full-length JAM-A cDNA or vector control. B Cell viability of hPS1 vector control (hPS1_vector) or hPS1 expressing the full-length JAM-A cDNA (hPS1_fullJAM) after infection with R124 or jin-3 at indicated MOIs, 3 days post-infection. Student’s T-test, ** = P ≤ 0.01. C JAM-A expression on primary pancreatic fibroblasts (Wildtype) or CRISPR/Cas9-mediated JAM-A KO fibroblasts. D Cell viability of wildtype or JAM-A KO fibroblasts after infection with R124 or jin-3 at indicated MOIs, 5 days post-infection. Student’s T-test, ** = P ≤ 0.01.