Table 1.
14 days | p-value | 28 days | p-value | ||
---|---|---|---|---|---|
Gender | Male (n = 101) | 1736.9 (1344.9–2243.0) | 0.301 | 1192.3 (943.5–1506.7) | 0.189 |
Female (n = 298) | 1474.7 (1257.3–1729.6) | 989.3 (858.0–1140.6) | |||
Local erythema | Yes (n = 23) | 3575.0 (2713.8–4709.5) | <0.001∗ | 2126.1 (1624.7–2782.2) | <0.001∗ |
No (n = 376) | 1459.7 (1267.8–1680.7) | 992.6 (874.5–1126.6) | |||
Local swelling | Yes (n = 41) | 3256.6 (2591.7–4092.0) | <0.001∗ | 1939.8 (1557.2–2416.3) | <0.001∗ |
No (n = 358) | 1410.4 (1218.8–1632.1) | 967.2 (848.4–1102.6) | |||
Local Pain | Yes (n = 326) | 1889.5 (1647.9–2166.5) | <0.001∗ | 1236.7 (1092.7–1399.7) | <0.001∗ |
No (n = 74) | 611.4 (430.5–868.1) | 474.0 (345.9–649.6) | |||
Fever ≥ 38 °C | Yes (n = 136) | 2894.0 (2479.5–3377.6) | <0.001∗ | 1791.0 (1552.9–2065.7) | <0.001∗ |
No (n = 263) | 1108.1 (928.4–1322.6) | 781.2 (666.4–915.8) | |||
Arthralgia/arthritis | Yes (n = 31) | 3236.4 (2621.5–3995.5) | <0.001∗ | 1920.1 (1578.2–2336.2) | <0.001∗ |
No (n = 368) | 1443.6 (1250.2–1666.9) | 984.7 (865.2–1120.7) | |||
Nausea/vomit | Yes (n = 22) | 2652.3 (1588.9–4427.5) | 0.055 | 1599.8 (1003.1–2551.6) | 0.090 |
No (n = 377) | 1488.9 (1294.7–1712.2) | 1011.3 (891.9–1146.6) | |||
Chills | Yes (n = 158) | 2466.8 (2084.5–2919.1) | <0.001∗ | 1544.4 (1326.3–1798.4) | <0.001∗ |
No (n = 241) | 1127.2 (936.5–1356.8) | 800.3 (677.1–945.9) | |||
Headache | Yes (n = 179) | 1899.0 (1594.8–2261.2) | 0.004∗ | 1213.7 (1039.7–1416.9) | 0.019∗ |
No (n = 220) | 1294.1 (1061.4–1577.7) | 913.4 (763.1–1093.4) | |||
Myalgia | Yes (n = 292) | 2067.9 (1803.2–2371.4) | <0.001∗ | 1347.8 (1191.3–1524.9) | <0.001∗ |
No (n = 107) | 684.1 (511.5–914.8) | 508.8 (391.8–660.7) | |||
Fatigue | Yes (n = 299) | 1885.6 (1633.1–2177.1) | <0.001∗ | 1242.4 (1091.4–1414.2) | <0.001∗ |
No (n = 100) | 834.3 (618.2–1125.8) | 605.9 (463.4–792.1) | |||
Systemic Rash | Yes (n = 30) | 1786.4 (1065.8–2994.2) | 0.534 | 1113.1 (712.4–1739.2) | 0.745 |
No (n = 369) | 1518.4 (1319.1–1747.7) | 1031.3 (908.5–1170.7) |
IgG: immunoglobulin G, BAU/mL: binding antibody units/mL, CI: confidence interval.