Table 1.
Summary of serum: NELF IgG partition ratio (percent) using the median dilution (5.01) factor in baseline-seronegative participants following AZD1222 vaccination
| Summary Statistics | Day 1 | Day 15 | Day 29 | Day 43 | Day 57 |
|---|---|---|---|---|---|
| N | 1,875 | 903 | 1,101 | 899 | 1,212 |
| Partition ratio geometric mean | 4.53 | 1.06 | 1.24 | 1.10 | 1.20 |
| 95% CI for geometric mean | (4.33, 4.75) | (0.97, 1.16) | (1.14, 1.35) | (1.00, 1.21) | (1.11, 1.30) |
| Geometric %CV | 1.38 | 2.29 | 2.35 | 2.48 | 2.62 |
| Min | 0.05 | 0.01 | 0.01 | 0.00 | 0.00 |
| Max | 262.31 | 49.67 | 265.36 | 51.80 | 14,138.06 |
CI, confidence interval; CV, coefficient of variation; IgG, immunoglobulin G; Max, maximum; Min, minimum; NELF, nasal epithelial lining fluid.
In order to provide comprehensive information on durability of immunogenicity post vaccination, data was censored in study participants at time of receipt of non-study COVID-19 vaccine, if applicable, but not at time of unblinding.