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. 2021 Sep 12;38(6):1027–1045. doi: 10.1007/s10565-021-09650-9

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — High expression of CTSLP8 in OC tissues was associated with chemotherapy response and overall survival. A In situ hybridization experiments demonstrated the expression of CTSLP8 with different chemotherapy response on tissue chips. B Representative immunohistochemistry staining demonstrated the expression of the c-Myc with different chemotherapy response on tissue chips. C–D The mean fluorescence intensity (MFI) and H-score were used to quantify the expressions of CTSLP8 and c-Myc, respectively. E The correlation between mean fluorescence intensity (MFI) of CTSLP8 and H-score of c-Myc. F Patients with OC with a high CTSLP8 expression exhibited a significantly low overall survival. G Patients with OC with a high c-Myc expression exhibited a significantly low overall survival. H Diagram illustrating our conclusions