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. 2022 Oct 19;17(1):172–184. doi: 10.1038/s41396-022-01333-5

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Comparison of the functional differences in genome properties, Kyoto Encyclopedia of Genes and Genomes (KEGG) orthologous groups, and carbohydrate-active enzymes between BSH-carrying and non-BSH-carrying MAGs belonging to the family Acutalibacteraceae (A) and genus Alistipes (B). GenProp0918 (GP0918), Anaerobic sulfatase/maturase system; GP1590, 4-Amino-2-methyl-5-diphosphomethylpyrimidine biosynthesis; GP1266, Superpathway of thiamine diphosphate biosynthesis II; GP1619, L-histidine degradation I; GP1613, Formate assimilation into 5,10-methylenetetrahydrofolate; GP0689, Glyoxalate conversion to phosphoglycerate; GP0914, [FeFe]-dependent hydrogenase; GP1606, Octopamine biosynthesis;GP1442, Protein O-[N-acetyl]-glucosylation; K06381, spoIID, stage II sporulation protein D; K07029, dagK, diacylglycerol kinase (ATP); K07699, spo0A, stage 0 sporulation protein A; K20509, madB, carboxybiotin decarboxylase; K19355, MAN, mannan endo-1,4-beta-mannosidase; K01206, FUCA, alpha-L-fucosidase; K03150, thiH, 2-iminoacetate synthase; K01468, hutI, imidazolonepropionase.