Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Oct 19;17(1):172–184. doi: 10.1038/s41396-022-01333-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 6 — Histology (A) and mucosal thickness (B) of the colon. C Gene ontology (GO) analysis based on differentially expressed genes (DEGs). Upregulated GO terms are in red; unchanged GO terms are in green; downregulated GO terms are in blue. D Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis of DEGs. bta04610, Complement and coagulation cascades; bta00140, Steroid hormone biosynthesis; bta03320, PPAR signaling pathway; bta04975, Fat digestion and absorption; bta04979, Cholesterol metabolism; bta04976, Bile secretion; bta00590, Arachidonic acid metabolism; bta00591, Linoleic acid metabolism. E DEGs related to complement system. MAC, membrane attack complex. Significantly different genes encoding enzymes involved in the related pathways are shown in red (upregulation in the grain-fed animals) and blue (downregulation in the grain-fed animals). z score = (up-down)/count^(1/2), wherein, up, down, and count respectively represent the number of upregulated, downregulated, total DEGs in related GO or KEGG terms.