Table 2.

Adjusted HRs for the association between continuous relative amplitude and brain disorder incidents.

		Model 1		Model 2
	Events	HR (95% CI)	p-value	HR (95% CI)	p-value
All-cause dementia	262	1.22 (1.14–1.29)	<0.001	1.23 (1.15–1.31)	<0.001
Alzheimer’s disease	115	1.12 (0.98–1.28)	0.102	1.16 (1.01–1.33)	0.036*
Parkinson’s disease	190	1.28 (1.22–1.35)	<0.001	1.33 (1.25–1.41)	<0.001
Stroke	481	1.14 (1.07–1.22)	<0.001	1.13 (1.06–1.22)	<0.001
Depression	1102	1.23 (1.18–1.27)	<0.001	1.18 (1.13–1.23)	<0.001
Anxiety	1161	1.16 (1.11–1.21)	<0.001	1.14 (1.09–1.20)	<0.001

Model 1 was adjusted by age, sex, Townsend deprivation index, ethnicity, and wear season. Model 2 was additionally adjusted by educational attainment, smoking status, alcohol consumption status, physical activity, BMI, and ApoE-ε4 allele.

*p-value not significant after Bonferroni correction (α = 0.05/6).