Table 1.
Characteristics of the cancer clinical trials (n = 508) identified by a systematic search of the online database ‘clinicaltrials.gov’ between February 2022 and May 2022 in a study that aimed to determine the current landscape of cancer clinical trials in Ukraine and Russia and estimate the number of cancer clinical trials at risk as a result of the conflict.
| Characteristics | Total study cohort | Trial sites |
|
|---|---|---|---|
| Russia | Ukraine | ||
| Study site | 508 | 474 (93) | 192 (38) |
| Phase of study | |||
| Phase 1 | 22 (4) | 17 (4) | 10 (5) |
| Phase 2 | 106 (21) | 93 (20) | 34 (18) |
| Phase 3 | 344 (68) | 330 (70) | 143 (75) |
| Phase 4 | 12 (2) | 12 (3) | 3 (2) |
| Recruiting status | |||
| Not yet recruiting | 4 (1) | 2 (<1) | 2 (1) |
| Recruiting | 246 (48) | 229 (48) | 99 (52) |
| Enrolling by invitation | 7 (1) | 7 (1) | 0 (0) |
| Active, not recruiting | 251 (49) | 236 (50) | 91 (47) |
| Sample size | |||
| Phase 1 | 104 (30–500) | 104 (30–500) | 138 (30–500) |
| Phase 2 | 200 (4–1595) | 200 (8–1595) | 168 (4–1000) |
| Phase 3 | 624 (12–5637) | 644 (12–5637) | 682 (60–5637) |
| Phase 4 | 280 (81–1036) | 334 (81–1036) | 387 (160–1000) |
| Sponsorship type | |||
| Commercial only | 454 (89) | 426 (90) | 178 (93) |
| Non-commercial only | 36 (7) | 32 (7) | 5 (3) |
| Both | 18 (4) | 16 (3) | 9 (5) |
| Treatment intention | |||
| Advanced/palliative | 379 (75) | 353 (74) | 145 (76) |
| Curative | 129 (25) | 121 (26) | 47 (24) |
Data presented as n of studies (%) or median (range).