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. 2022 Nov 14;14(11):e31508. doi: 10.7759/cureus.31508

Table 3. Proportion of patients with clinical improvement from baseline .

**P-values were obtained by using ANCOVA.

mITT = modified intent-to-treat; PP = protocol population; EOT = end of treatment; ANCOVA = analysis of covariance

Visit Molnupiravir (N = 608), n (%) Standard of care (N = 610), n (%) Proportional difference (95% confidence interval) Molnupiravir versus standard of care (p-value**) Molnupiravir (N = 593), n (%) Standard of care (N = 581), n (%) Proportional difference (95% confidence interval) Molnupiravir versus standard of care (p-value**)
mITT population PP population
Day 5 (EOT) 491 (80.76) 196 (32.13) -48.6 (-53.5, -43.8) <0.0001 489 (82.46) 194 (33.39) -49.1 (-54.0, -44.2) <0.0001
Day 10 581 (95.56) 453 (74.26) -21.3 (-25.1, -17.5) <0.0001 574 (96.80) 445 (76.59) -20.4 (-24.1, -16.7) <0.0001
Day 14 592 (97.37) 576 (94.10) -3.3 (-5.5, -1.0) 0.0066 585 (98.65) 558 (96.04) -2.6 (-4.4, -0.8) 0.0059