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. 2022 Dec 14;12:21635. doi: 10.1038/s41598-022-26212-z

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Suppression of A549 cell invasion by compounds 4d, 4h, and 4i. (a) Representative images of invaded A549 cells after treatment with various nontoxic concentrations (5, 10, and 15 μM) of compounds 4d, 4h, and 4i for 24 h. (b) Quantitative analysis of invaded cell numbers in each group. Representative images from three independent experiments are shown (n = 3). Data represent the mean ± SD. *p < 0.05; **p < 0.01; ***p < 0.001 compared with DMSO-treated A549 cells.