TABLE 2.

Description of different selected models.

Cluster	Model	Distance loop 1–3 (Å)	Distance loop 7–3 (Å)	DOPE score	Structure
1	330	35.10	31.22	–63218.02	Wide open structure, shorter helix TM5
	286	35.09	31.21	–62557.37	Wide open structure, optimal alpha helices
2	127	33.57	26.64	–63548.59	Normal structure, no helix TM6b, shorter helix TM5
	189	33.73	26.72	–63208.85	Normal structure, no helix TM6b, optimal alpha helices
	283	34.122	26.77	–63361.71	Normal structure, optimal alpha helices
3	259	30.06	25.78	–65333.53	Close structure, no helix TM6b
	140	30.19	25.89	–64438.16	Close structure, optimal alpha helices
	136	30.97	26.43	–64037.43	Close structure, optimal alpha helices