Table 3.
Overall (n =1058) | Obesity (n =708) | Lean (n =188) | T2DM (n =162) | |||||
---|---|---|---|---|---|---|---|---|
Indicators | MAFLD (n =621) | Non-MAFLD (n =437) | MAFLD (n =464) | Non-MAFLD (n =244) | MAFLD (n =36) | Non-MAFLD (n =152) | MAFLD (n =121) | Non-MAFLD (n =41) |
BMI | 29.29 ± 4.87 | 24.20 ± 3.09 * | 28.47 ± 2.90 | 26.13 ± 2.19 * | 22.68 ± 0.35 | 21.04 ± 1.42 * | 34.39 ± 6.93 | 24.41 ± 2.66 * |
AI1 | 3.25 ± 0.99 | 2.49 ± 0.88 * | 3.20 ± 0.95 | 2.67 ± 0.89 * | 2.97 ± 1.08 | 2.17 ± 0.78 * | 3.53 ± 1.06 | 2.62 ± 0.91 * |
AI2 | 2.56 ± 0.80 | 2.03 ± 0.72 * | 2.56 ± 0.78 | 2.20 ± 0.74 * | 2.43 ± 0.98 | 1.79 ± 0.64 * | 2.61 ± 0.84 | 1.91 ± 0.68 * |
non-HDL-C | 3.67 ± 0.86 | 3.21 ± 0.85 * | 3.63 ± 0.84 | 3.27 ± 0.81 * | 3.67 ± 1.08 | 3.06 ± 0.87 * | 3.82 ± 0.86 | 3.42 ± 1.00 * |
R-CHR | 4.25 ± 0.99 | 3.49 ± 0.88 * | 4.20 ± 0.95 | 3.67 ± 0.89 * | 3.97 ± 1.08 | 3.17 ± 0.78 * | 4.53 ± 1.06 | 3.62 ± 0.91 * |
AIP | 0.24 ± 0.26 | -0.09 ± 0.28 * | 0.21 ± 0.26 | -0.02 ± 0.27 * | 0.18 ± 0.24 | -0.22 ± 0.24 * | 0.35 ± 0.23 | -0.06 ± 0.30 * |
LCI | 30.75 ± 23.67 | 13.27 ± 13.18 * | 29.03 ± 23.17 | 15.33 ± 13.42 * | 27.87 ± 22.21 | 9.34 ± 8.99 * | 38.20 ± 24.68 | 15.59 ± 20.12 * |
BLCI1 | 0.37 ± 0.15 | 0.34 ± 0.14 * | 0.37 ± 0.15 | 0.34 ± 0.14 * | 0.44 ± 0.17 | 0.34 ± 0.14 * | 0.36 ± 0.16 | 0.33 ± 0.13 |
BLCI2 | 0.22 ± 0.10 | 0.20 ± 0.09 * | 0.22 ± 0.10 | 0.20 ± 0.09 * | 0.26 ± 0.12 | 0.19 ± 0.09 * | 0.21 ± 0.10 | 0.17 ± 0.08 |
TG/HDL-C | 2.06 ± 1.25 | 1.00 ± 0.78 * | 1.94 ± 1.21 | 1.16 ± 0.85 * | 1.79 ± 1.13 | 0.71 ± 0.44 * | 2.58 ± 1.34 | 1.14 ± 1.00 * |
BAI | 31.38 ± 6.54 | 26.38 ± 4.21 * | 30.94 ± 6.32 | 26.89 ± 4.11 * | 28.79 ± 7.55 | 25.59 ± 4.52 * | 33.87 ± 6.43 | 26.20 ± 3.04 * |
BRI | 5.18 ± 1.67 | 3.46 ± 1.01 * | 4.80 ± 1.10 | 3.90 ± 0.87 * | 4.04 ± 1.22 | 2.67 ± 0.78 * | 6.98 ± 2.25 | 3.76 ± 0.72 * |
LAP | 92.37 ± 90.87 | 30.56 ± 30.64 * | 76.42 ± 59.25 | 38.75 ± 35.26 * | 66.15 ± 53.04 | 16.32 ± 12.42 * | 161.34 ± 149.37 | 34.62 ± 30.01 * |
VAI | 3.07 ± 1.90 | 1.44 ± 1.05 * | 2.80 ± 1.72 | 1.63 ± 1.14 * | 3.23 ± 2.17 | 1.10 ± 0.67 * | 4.08 ± 2.12 | 1.57 ± 1.29 * |
WTI | 246.43 ± 220.71 | 108.78 ± 84.09 * | 217.66 ± 160.22 | 126.80 ± 95.40 * | 203.44 ± 157.54 | 75.87 ± 40.21 * | 369.54 ± 355.49 | 123.54 ± 96.70 * |
WWI | 10.82 ± 0.80 | 10.22 ± 0.73 * | 10.68 ± 0.71 | 10.29 ± 0.65 * | 11.18 ± 1.18 | 10.02 ± 0.84 * | 11.28 ± 0.78 | 10.53 ± 0.46 * |
CVAI | 142.55 ± 47.80 | 78.04 ± 45.61 * | 134.80 ± 35.49 | 96.84 ± 38.44 * | 95.28 ± 23.38 | 39.54 ± 33.33 * | 186.32 ± 62.85 | 108.93 ± 27.03 * |
FLI | 10.05 ± 17.11 | 1.16 ± 2.36 * | 5.99 ± 7.86 | 1.75 ± 2.93 * | 1.11 ± 0.93 | 0.20 ± 0.25 * | 28.24 ± 29.20 | 1.17 ± 1.64 * |
ZJU index | 43.35 ± 7.10 | 35.01 ± 4.20 * | 41.62 ± 4.21 | 37.10 ± 3.22 * | 35.69 ± 1.98 | 31.04 ± 2.17 * | 52.26 ± 9.05 | 37.24 ± 4.45 * |
TyG index | 1.80 ± 0.70 | 1.04 ± 0.58 * | 1.66 ± 0.59 | 1.13 ± 0.55 * | 1.67 ± 0.51 | 0.79 ± 0.48 * | 2.40 ± 0.83 | 1.44 ± 0.70 * |
FLDI | 37.14 ± 6.36 | 29.12 ± 4.30 * | 35.94 ± 4.20 | 31.47 ± 3.28 * | 29.35 ± 1.94 | 24.95 ± 2.25 * | 44.08 ± 8.22 | 30.59 ± 3.84 * |
CMI | 1.21 ± 0.79 | 0.52 ± 0.43 * | 1.11 ± 0.71 | 0.62 ± 0.48 * | 0.95 ± 0.60 | 0.33 ± 0.21 * | 1.70 ± 0.92 | 0.60 ± 0.55 * |
Data were expressed as mean ± standard deviation ( ) and analyzed by student’s t-test for continuous variables.
compared with MAFLD in respective subgroups, *P < 0.05.
MAFLD, metabolic dysfunction-associated fatty liver disease; T2DM, type 2 diabetes mellitus; BMI, body mass index; AI, atherosclerosis index; HDL-C, high-density lipoprotein cholesterol; R-CHR, coronary heart index; AIP, atherogenic index of plasma; LCI: lipid comprehensive index; BLCI, bilirubin lipid composite index; TG, triglyceride; BAI, body adiposity index; BRI, body roundness index; LAP, lipid accumulation product; VAI, visceral fat index; WTI, waist triglyceride index; WWI, weight-adjusted waist index; CVAI, Chinese visceral adiposity index; FLI, fatty liver index; ZJU index, Zhejiang University index; TyG index, triglyceride-glucose index; FLDI, fatty liver disease index; CMI, cardiometabolic index.