Table 4.
ROC analysis of indices in predicting the risk of MAFLD in different groups.
| Indexes | AUC | 95%CI | Sensitivity(%) | Specificity(%) | Youden index | Cutoff points | |
|---|---|---|---|---|---|---|---|
| MAFLD | |||||||
| FLI | 0.879 * | (0.857,0.898) | 88.57 | 72.31 | 0.6088 | 0.915 | |
| LAP | 0.873 * | (0.851,0.892) | 86.15 | 72.54 | 0.5869 | 56.505 | |
| BMI | 0.836 | (0.812,0.858) | 84.38 | 65.90 | 0.5028 | 25.391 | |
| Obesity MAFLD |
|||||||
| ZJU index | 0.816 * | (0.786,0.844) | 71.12 | 80.33 | 0.5145 | 39.139 | |
| LAP | 0.796 * | (0.765,0.826) | 64.01 | 82.79 | 0.4680 | 50.700 | |
| BMI | 0.748 | (0.715,0.780) | 62.50 | 72.54 | 0.3504 | 27.143 | |
| Lean MAFLD | |||||||
| ZJU index | 0.952 * | (0.912,0.978) | 88.89 | 89.47 | 0.7836 | 33.706 | |
| WTI | 0.920 | (0.872,0.954) | 80.56 | 89.47 | 0.7003 | 120.120 | |
| BMI | 0.890 | (0.836,0.931) | 86.11 | 83.55 | 0.6966 | 22.477 | |
| T2DM MAFLD | |||||||
| BRI | 0.963 | (0.921,0.986) | 81.82 | 100.00 | 0.8182 | 4.970 | |
| FLI | 0.958 | (0.915,0.983) | 90.91 | 87.80 | 0.7871 | 2.071 | |
| BMI | 0.953 | (0.909,0.980) | 96.69 | 78.05 | 0.7474 | 25.992 |
The predictive abilities of indicators were analyzed by ROC.
compared with BMI in respective subgroups, *P < 0.05.
MAFLD, metabolic dysfunction-associated fatty liver disease; T2DM, type 2 diabetes mellitus; ROC, receiver operating characteristic; AUC, areas under the curve; CI, confidence interval; FLI, fatty liver index; LAP, lipid accumulation product; BMI, body mass index; ZJU index, Zhejiang University index; WTI, waist triglyceride index; BRI, body roundness index.