Skip to main content
. 2022 Dec 1;3:1068455. doi: 10.3389/fragi.2022.1068455

FIGURE 2.

FIGURE 2

5-HT2A modulates the protein consumption set-point. (A) As dietary yeast increases, both 5-HT2A −/− mutants and w-; CS controls consume less (n = 10 where each replicate is comprised of 10 flies, ANCOVA Diet: p < 0.001 Genotype: p = 0.003 Interaction: p = 0.242), and when these data are scaled to represent the mass of protein consumed across diets, (B) 5-HT2A −/− mutants show a decreased protein consumption target across diets (n = 10 where each replicate is comprised of 10 flies, ANCOVA Diet: p = 0.322 Genotype: p < 0.001 Interaction: p = 0.605). Relative to controls, 5-HT2A −/− mutants show no differences from controls in the (C) total volume (n = 8–10 where each replicate is comprised of 10 flies, ANCOVA Diet: p < 0.001 Genotype: p = 0.263 Interaction: p = 0.594) or (D) mass of sucrose consumed across three different concentrations of a sucrose-only diet (n = 8–10 where each replicate is comprised of 10 flies, ANCOVA Diet: p < 0.001 Genotype: p = 0.409 Interaction: p = 0.996). All experiments were conducted in females.