Table 2.
Perinatal outcomes among MS-OHSS patients and Non-OHSS patients before propensity score matching.
| MS-OHSS singleton pregnancies (n = 114) | Non-OHSS singleton pregnancies (n = 3,898) | Odds ratio/mean difference(95% CI) | Adjusted odds ratio/mean difference (95% CI) | |
|---|---|---|---|---|
| Obstetric outcomes | ||||
| Placenta previa (%) | 0(0.00) | 38(0.97) | - | - |
| Placenta abruption (%) | 0(0.00) | 17(0.44) | - | - |
| Premature rupture of membranes (%) | 4(3.51) | 140(3.59) | 0.98(0.35-2.68) | 1.04(0.37-2.89) |
| Hypertensive disorders in pregnancy (%) | 4(3.51) | 156(4.00) | 0.87(0.32-2.40) | 1.07(0.39-2.98) |
| Gestational diabetes mellitus (%) | 5(4.39) | 356(9.13) | 0.46(0.19-1.13) | 0.57(0.23-1.41) |
| Cesarean delivery (%) | 73(64.04) | 2,508(64.34) | 0.91(0.62-1.34) | 1.10(0.74-1.64) |
| Neonatal outcomes | ||||
| Normal term infant (%) | 98(85.96) | 3,232(82.91 | 1.26(0.74-2.16) | 1.15(0.67, 1.98) |
| Gestational age (week) | 39.17 ± 1.30 | 39.03 ± 1.63 | 0.13(-0.17-0.44) | 0.05(-0.26-0.35) |
| Premature delivery (%) | 6(5.26) | 273(7.00) | 0.74(0.32-1.69) | 0.83(0.36-1.92) |
| Birth weight (g) | 3315.35 ± 439.30 | 3368.90 ± 521.04 | -53.55(-150.22-43.11) | -47.37(-143.81-49.08) |
| Low birth weight (%) | 4(3.51) | 154(3.95) | 0.88(0.32-2.43) | 0.98(0.35-2.70) |
| Very low birth weight (%) | 0(0.00) | 25(0.64) | - | - |
| Macrosomia (%) | 6(5.26) | 318(8.16) | 0.63(0.27-1.43) | 0.67(0.29-1.54) |
| SGA (%) | 4(3.51) | 75(1.92) | 1.85(0.67-5.16) | 1.76(0.62-4.98) |
| LGA (%) | 26(22.81) | 1,101(28.25) | 0.75(0.48-1.17) | 0.85(0.54-1.33) |
| Admitted in pediatrics (%) | 1(0.88) | 70(1.80) | 0.48(0.07-3.51) | 0.58(0.08-4.26) |
| Birth defect (%) | 1(0.88) | 46(1.18) | 0.74(0.10-5.42) | 0.88(0.12-6.57) |
| Birth height (cm) | 50.22 ± 1.49 | 50.24 ± 2.06 | -0.02(-0.40-0.36) | -0.01(-0.39-0.38) |
| 1-minute Apgar scores | 10.00 ± 0.00 | 9.96 ± 0.38 | 0.04(-0.03-0.11) | 0.05(-0.02-0.12) |
Data are presented as mean ± standard deviation or n (%). logistic regression and linear regression were used to calculate odds ratio (95% CI) and mean difference (95% CI). Adjusted odds ratio (95% CI) and mean difference (95% CI) adjusted for maternal age, maternal body mass index, basal serum FSH level, basal serum AMH level, type of stimulation protocol, basal antral follicle count, number of oocytes retrieved, day of embryo development for embryo transfer, number of embryo transferred. MS-OHSS, moderate-to-severe-ovarian hyperstimulation syndrome; CI, confidence interval; -, not applicable; SGA, small for gestational age; LGA, large for gestational age.