Table 2.
Markers of cell damage, neutrophil, and macrophage activation in patients with different outcome
| Total (N=156) | Discharged (N=107) | Deceased (N=49) | p-value | |
|---|---|---|---|---|
| Alu 115 (n-cfDNA ) pg/μla, median(IQR) | 361.7 (154.2-1041.9) | 340.3 (163.9-1036.3) | 385.2 (145.5-1109.1) | 0.953 |
| Alu 247 (n-cfDNA) pg/μla, median(IQR) | 136.9 (52.6-519.8) | 163.4 (51.9-719.2) | 109.7 (53.3-378.0) | 0.449 |
| Alu 247/115 (n-cfDNA integrity), median(IQR) | 0.44 (0.33-0.77) | 0.50 (0.30-0.72) | 0.33 (0.22-0.62) | 0.031 |
| MT-CO3 (mt-cfDNA ) pg/μlb, median(IQR) | 2.38 (1.12-5.22) | 2.09 (1.00-5.13) | 2.52 (1.48-6.23) | 0.571 |
| NE ng/ml , median(IQR) | 105.1 (56.5-173.0) | 94.0 (47.7-154.0) | 115.7 (84.2-212.7) | 0.009 |
| LL-37 ng/mL), median(IQR) | 39.0 (26.8-55.6) | 36.9 (26.5-53.0) | 44.3 (31.8-58.0) | 0.194 |
| sCD163 ng/mL median(IQR) | 647.6 (441.0-951.9) | 614.0 (370.0-821.0) | 787.0 (560.0-1304.0) | 0.002 |
aAbsolute equivalent amount of genomic DNA/μl in the extracted sample. bAbsolute equivalent amount of the template (mitochondrial) DNA in the extracted sample. Font in bold: significant p-value