TABLE 3.

Engineered exosomes in the cardiovascular system.

Disease type	Encapsulated contents	Function
Atherosclerosis	HAL	Enhanced anti-inflammatory effects of HAL for fluorescence imaging of hardened plaques
Acute myocardial infarction	miR-93-5p	Protection of the infarct-induced myocardial injury
	IMTP	Targeted ischemic myocardium to treat myocardial infarction
	MIF	Enhance cell proliferation, angiogenesis, and inhibit cardiomyocyte apoptosis
Ischemic-Reperfusion Injury	miR-125b	Targeted SIRT7 to mitigate myocardial injury
	Curcumin	Neurovascular vessels were recovered after ischemia and reperfusion