Table 6.
Agreement between 24-hour creatinine clearance and iGFR in the replication cohort
| Lower threshold | Upper threshold | Qualifying participants N (%) |
RMSE (ml/min) | P30 (%)a |
|---|---|---|---|---|
| No exclusions | 714 (100.0) | 20.8 | 69.0 | |
| Model based exclusionsb | ||||
| None | Upper 97.5% | 690 (96.6) | 16.7 | 70.4 |
| None | Upper 95% | 682 (95.5) | 16.7 | 70.5 |
| Lower 2.5% | Upper 97.5% | 660 (92.4) | 15.3 | 73.0 |
| Lower 5% | Upper 97.5% | 646 (90.5) | 14.3 | 74.1 |
| Lower 7.5% | Upper 97.5% | 629 (88.1) | 14.0 | 75.7 |
| Lower 10% | Upper 97.5% | 617 (86.4) | 13.8 | 76.3 |
| Lower 5% | Upper 95% | 638 (89.4) | 14.2 | 74.3 |
| Lower 7.5% | Upper 95% | 621 (87.0) | 13.9 | 75.8 |
| Existing limits | ||||
| 15 mg/kg women | 20 mg/kg women | 182 (25.5) | 14.6 | 74.2 |
| 20 mg/kg men | 25 mg/kg men |
iGFR, glomerular filtration rate measured by 125I-iothalamate clearance; RMSE, root mean squared error.
a
Proportion of values within 30% of predicted.
b
Based on final anthropometric and demographic model (model 1).