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. 2021 Mar 23;161(2):414–421. doi: 10.1016/j.ygyno.2021.02.026

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Fig. 5 — Adjusted associations between CCRT wait-time and all-cause mortality (brachytherapy stratification).

Adjusted-hazard ratios for all-cause mortality are shown by week of CCRT wait-time for (A) external beam and brachytherapy and (B) external beam without brachytherapy. CCRT wait-time was coded using restricted cubic spline transformation with four knots located at 4, 8, 12, and 16 weeks (shown as knots). The Y-axis represents the effect size for all-cause mortality. The X-axis represents the wait-time (week) from cervical cancer diagnosis to CCRT initiation. Week 6 is set as the referent group. The solid line represents the estimate as effect size. The dashed lines are 95% confidence interval. Abbreviation: CCRT, concurrent chemo-radiotherapy; aHR-adjusted-hazard ratio; and CI, confidence interval.