TABLE 2.
Inhibition of D9 macrophage RNI production by catalase C-10 correlates with the production of ornithinea
| Catalase (U/ml) | % Increase in ornithine production | NO2− (nmol/106 cells) |
|---|---|---|
| No addition | NDb | 113.7 |
| C-10 (2,600) | 111.6 | 5.2 |
| C-10 (260) | 78.6 | 31.9 |
| C-10 (26) | 6.0 | 77.7 |
Experiments were carried out as described in footnote a of Table 1. Ornithine contents were quantitated as described previously (6, 10). Percent increase in ornithine production = [(ornithine level in activated macrophage culture with catalase/ornithine level in activated macrophage culture without catalase) − 1] × 100. Data shown are representative of two experiments.
ND, not done.