Fig. 4.

The effect of the β-glucan extracts on gene expression levels of THP-1 macrophages (PMA differentiated), relative to PBS-treated cells (expression level = 1.0). Panel A; TLR2, Panel B; IL-10, Panel C; CLEC7a, Panel D; CCL8. Differences in relative gene expression *p < 0.05 versus PBS; ^#p < 0.05 versus LPS. Cells were treated with 1 mg/mL of extracts for 24 h before analysis of gene expression levels. Phosphate buffer saline (PBS), Commercial Lentinan (C.L.E.), Lentinus edodes (L.E), Pholiota microspora (P.M), Pleurotus ostreatus (P.O), Pleurotus citrinopileatus (P.C), Pleurotus eryngii (P.E), Hypsizygus tessellatus (H.T) and Agaricus blazeii (A.B).