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. 2022 Dec 1;13:1053556. doi: 10.3389/fphar.2022.1053556

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Copyright © 2022 Zhou, Cao, Diao, Wang, Long, Wang and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Noncoding RNA in tumors. There are two types of non-coding RNAs (ncRNAs) in tumor cells: short/small ncRNAs and long ncRNAs. Short/small ncRNAs include at least four types: microRNAs (miRNAs), small nucleolar RNAs (snoRNAs), transfer RNA-derived small RNAs (tsRNAs), and piwi-interacting RNAs (piRNAs). Long ncRNAs include common lncRNAs, circular RNAs (circRNAs), and pseudogenes. These ncRNAs are aberrantly expressed in all types of human cancers and are involved in tumor progression, including tumor occurrence, development, recurrence, drug resistance, invasion, and metastasis.