Table 2.

Comparison between Glycogenic Hepatopathy and Non-Alcoholic Fatty Liver Disease (NAFLD).

	Glycogenic Hepatopathy	Non-Alcoholic Fatty Liver Disease
Age at onset	Mostly children and adolescents	Mostly Adults
Uncontrolled T1D with extremely poor glucose control	Yes	Not necessarily
Symptoms	Present (abdominal discomfort)	Uncommon
Signs	Tender hepatomegaly	Ascites in advanced NAFLD
Liver Enzymes	Mild to severe elevation	No or mild elevation (mostly alanine transaminase)
Ultrasonography findings	Hyperechogenic: due to glycogen deposition	Hyperechogenic: due to fat deposition
Magnetic Resonance Imaging findings	Absence of steatosis (no difference in intensities)	Presence of steatosis (difference in intensities)
Diagnosis: Gold Standard	Histology (liver biopsy)	Histology (liver biopsy)

T1D, type 1 diabetes.