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. 2022 Dec 1;13:1060668. doi: 10.3389/fphar.2022.1060668

TABLE 2.

Baseline characteristics of studies with the control group.

Reference Area (R)-CDOP (R)-CHOP Population Cycles (n) Interval (days) Median follow-up (months) Toxicity grading system Outcome indicators
N Median age (years) Female (%) N Median age (years) Female (%)
Zhou (2015) China 41 67 51 62 68 45 DLBCL 6 21 28 CTCAE 3.0 ①③④
Shao et al. (2020) China 33 63 46 45 61 47 DLBCL 8 21 24 Grades NOS ①②③④
Zheng et al. (2018) China 21 62 48 21 62 43 NHL 6 21 36 Grades NOS ①②
Li et al. (2016) China 25 69 44 25 68 40 DLBCL 4–6 21 18 Grades NOS ①②③④
Huang and Luo (2016) China 25 47 50 25 44 60 DLBCL 6–8 21 24 CTCAE 4.0
Huang et al. (2021) China 15 54 47 15 54 40 NHL 4 NR NR Grades NOS
Ye, J (2022) China 44 48 46 44 46 50 NHL NR NR 6 Grades NOS
Chang and Zhu (2021) China 37 57 54 39 51 67 DLBCL NR 21 NR CTCAE 5.0 ①②
Li and Hu (2018) China 34 NR NR 30 NR NR DLBCL 6 21 NR WHO ①②③④
Wu et al. (2020) China 23 56 52 23 52 61 DLBCL 2 21 NR CTCAE 5.0 ①②③④
Liu et al. (2021) China 83 69 59 45 70 44 PTCL 6 21 12 Grades NOS

Abbreviations: DLBCL, diffuse large B-cell lymphoma; NHL, non-Hodgkin’s lymphoma; PTCL, peripheral T-cell lymphoma; NR, not reported; CTCAE, Common Terminology Criteria for Adverse Events; WHO, World Health Organization; NOS, not otherwise specified; and outcome indicators (① total cardiovascular adverse events; ② non-serious cardiovascular adverse events; ③ serious cardiovascular adverse events; and ④ heart failure).