Table 2.

Summary of changes in platelet parameters in patients with SARS-CoV-2 infection

Platelet parameter	Patients with SARS-CoV-2 infection	Clinical implications
Platelet count	Decreased in advanced stages of infection Increased (rare)	Pejorative prognostic marker of the disease Not defined
Mean platelet volumen (MPV)	Increased (> 10 fL)	Appears to predict the risk of developing thrombocytopenia and an increased risk of venous thromboembolism (VTE)
Immature platelet fraction (IPF)	Increased (> 8%)	Seems to predict evolution towards thrombocytopenia and increased risk of VTE Indicator of destruction and/or peripheral platelet consumption
Platelet distribution width (PDW)	Increased (> 11 fL)	Platelet activation marker and increased risk of thrombosis
Platelet/lymphocyte ratio (PLR)	Increased	Patients with severe COVID-19 have higher PLR levels than patients with mild/moderate disease
MPV/platelet count ratio (MPR)	Increased	Independent risk predictor for developing COVID pneumonia
Platelet function and aggregation	Hyperfunction	An increased thrombotic risk is attributed to it in some studies