Fig. 2. 500 MHz (a) 1D 1H spectrum, (b) 1H pure shift spectrum recorded using the unmodified Zangger–Sterk pulse sequence, (c) vertical expansion of the spectrum (b and d) 1H pure shift spectrum acquired with the pulse sequence modified to remove sidebands, for a mixture containing rosuvastatin (1) and 2.8% of its precursor BEM (2). (e) 1D 1H spectrum of BEM. Spectra c and d were acquired in approximately 9 h with an sw1 of 39.0625 Hz and 16 chunks using an RSNOB spatially selective spin inversion element with a peak RF amplitude of 47 Hz. Reproduced from ref. 25 with permission from the Royal Society of Chemistry.
