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. 2022 Dec 15;4:60. doi: 10.1186/s42466-022-00224-6

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Overview of origins of ALSFRS-R versions and variants and the collection process. A total of 20-ALS centers responded to the request to provide extant ALSFRS-R versions and variants. Nine different German variants and the original English version by Cedarbaum et al. [1] were collected. Translated variants differed in terms of wording. Two variants were designated for self-assessment. Several ALS centers use a shortened variant of the ALSFRS-EX [27]