Table 2.

Univariate and multivariate analysis of prognostic factors for survivals (by Cox regression)

Clinical factor	Progression-free survival				Overall survival
	Univariate		Multivariate		Univariate		Multivariate
	P	HR (95%CI)	P	HR (95%CI)	P	HR (95%CI)	P	HR (95%CI)
Age (≥ 60y, n = 23 vs. < 60y, n = 33)	0.78	1.12 (0.51–2.47)			0.86	0.93 (0.39–2.17)
Gender (male, n = 36 vs. female, n = 20)	0.82	0.91 (0.41–2.05)			0.12	1.93 (0.84–4.47)
Primary site (oral, n = 9 vs. extra oral, n = 47)	0.67	0.82 (0.33–2.04)			0.25	0.57 (0.22–1.47)
Ann Arbor stage (III/IV, n = 21 versus I/ II, n = 35)	0.27	1.58 (0.70–3.56)			0.03	2.58 (1.10–6.07)	0.66	1.32 (0.37–4.65)
B symptom (yes, n = 22 vs. no, n = 27)	0.36	0.65 (0.26–1.63)			0.38	0.66 (0.26–1.66)
LDH level (elevated, n = 17 versus normal, n = 24)	0.16	0.51 (0.19–1.32)			0.03	0.33 (0.12–0.91)	0.06	0.35 (0.12–1.05)
EBER (positive, n = 10 vs. negative, n =10)	0.37	0.60 (0.19–1.85)			0.21	0.49 (0.16–1.49)
Ki67 (≥ 80%, n = 40 vs. < 80%, n = 16)	0.34	0.63 (0.25–1.61)			0.56	0.75 (0.28–1.98)
Complete response (yes, n = 25 versus. No, n = 31)	0.001	3.51 (1.65–7.50)	0.003	3.89 (1.60–9.45)	0.001	7.03 (2.33–21.17)	0.002	13.24 (2.58–67.99)