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RALI-Dx biomarkers are associated with a) level of care provided (Kruskal–Wallis test) and b) 28-day mortality (Mann–Whitney U-test) in the Canada cohort. IL: interleukin; sTNFR1: soluble tumour necrosis factor receptor 1; sTREM1: soluble triggering receptor expressed on myeloid cells 1; ICU: intensive care unit. Box-and-whisker plots show median, interquartile range (IQR) and 1.5 times the IQR. *: p<0.05; **: p<0.01; ***: p<0.001; ****: p<0.0001.
