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. Author manuscript; available in PMC: 2022 Dec 15.
Published in final edited form as: Cell Rep. 2022 Nov 29;41(9):111718. doi: 10.1016/j.celrep.2022.111718

Figure 1. The genetic profile of ARC neurons reveals an orexigenic neuronal population expressing Drd1.

Figure 1.

(A) Batch-corrected, normalized expression values for Drd genes in each arcuate-median eminence (ARC-ME) neuron cluster from the Campbell et al., 2017 dataset.

(B) Number of Drd1 positive neurons from each cluster of ARC-ME neurons from A. Drd1 positive neurons from Agrp-expressing clusters are depicted in yellow.

(C) RNAscope images showing representative Drd1-expressing cells in the ARC with (▸) or without (▹) Agrp expression. Scale bar, 10 μm.

(D) Representative images showing the ARC of Drd1-Cre:GFP mice. Scale bar, 100 μm. Venn diagram indicates the average number of cells expressing only the Drd1-Cre:GFP (red), only Agrp (green), and both Drd1-Cre:GFP and Agrp (yellow). n = 3.