Table 2. Multivariable analysis of overall survival.
| Univariable | Multivariable | |||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| Age | 1.001 (0.986–1.016) | 0.925 | ||
| BMI | 0.990 (0.946–1.035) | 0.650 | ||
| Sex | ||||
| Male | Reference | |||
| Female | 0.698 (0.530–0.919) | 0.010 | ||
| Smoking history | 1.075 (0.815–1.416) | 0.610 | ||
| Drinking history | 1.124 (0.806–1.567) | 0.492 | ||
| History of hypertension | 1.000 (0.744–1.344) | 0.999 | ||
| Tumor location | ||||
| Head of pancreas | Reference | |||
| Pancreatic body/tail | 0.998 (0.711–1.399) | 0.989 | ||
| Tumor differentiation | ||||
| High/moderate | Reference | |||
| Low | 1.645 (1.187–2.279) | 0.003 | 1.589 (1.146–2.204) | 0.006 |
| Lymph node metastasis | 0.722 (0.514–1.015) | 0.061 | ||
| Tumor stage | ||||
| Phase I | Reference | |||
| Phase II | 1.119 (0.854–1.465) | 0.415 | ||
| Surgical approach | 0.996 | |||
| Radical pancreaticoduodenectomy | Reference | |||
| Distal pancreatectomy | 0.994 (0.707–1.398) | 0.973 | ||
| Other surgical procedures | 0.972 (0.496–1.905) | 0.934 | ||
| CA199 | ||||
| Normal | Reference | |||
| High | 1.170 (0.875–1.566) | 0.290 | ||
| Type 2 diabetes | 1.524 (1.134–2.048) | 0.005 | 1.475 (1.096–1.985) | 0.010 |