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. Author manuscript; available in PMC: 2022 Dec 15.
Published in final edited form as: Biomater Sci. 2020 Dec 10;9(3):653–657. doi: 10.1039/d0bm01713b

Figure 1. Light-activable micelles (LAMs) for the delivery of paclitaxel (PTX) to the tumor microenvironment (TME).

Figure 1.

Schematic representation of the enzyme-responsive LAMs. UV irradiation of inactive micelles (IMs) causes PTX cleavage and release into the hydrophobic pocket switching IMs to active micelles (AMs). Cleavage of the outer peptide shell by proteases results in a morphological switch and burst PTX release.