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. Author manuscript; available in PMC: 2022 Dec 15.
Published in final edited form as: Biomater Sci. 2020 Dec 10;9(3):653–657. doi: 10.1039/d0bm01713b

Figure 3. Enzyme-triggered size and morphology switch of LAMs.

Figure 3.

A) Size of inactive micelles (IMs), B) size of active micelles (AMs) before and C) after 18 h incubation with the model enzyme thermolysin as determined by dynamic light scattering (DLS) measurements. Changes in micelles morphology was investigated via both (D-F) dry state transmission electron microscopy (TEM) imaging (scale bars 200 nm), as well as confocal fluorescence microscopy of Cy5.5 labeled micelles in PBS G) before and H) after enzymatic cleavage. All settings were kept constant between images. Scale bars 50 μm and 10 μm