Table 3.
Vesicle Size, PDI, EE % and LE% of Different Niosomal Formulations Containing Letrozole (L1-L6). Data are Represented as Mean ± SD, n = 3
| Formulation | Vesicle Size (nm, Average ± SD) | Polydispersity Index (Average ± SD) | EE* (%) (Average ± SD) | LE** (%) (Average ± SD) |
|---|---|---|---|---|
| L1 | 242.90 ± 9.90 | 0.127 ± 0.023 | 94.4158 ± 0.0534 | 6.9095 ± 0.0082 |
| L2 | 186.70 ± 2.88 | 0.181 ± 0.012 | 96.0620 ± 0.0051 | 6.1518 ± 0.0113 |
| L3 | 190.30 ± 17.84 | 0.162 ± 0.007 | 97.9974 ± 0.0175 | 6.2864 ± 0.0067 |
| L4 | 301.73 ±19.23 | 0.213 ± 0.035 | 91.3281 ± 0.0304 | 3.4654 ± 0.0075 |
| L5 | 184.33 ± 7.35 | 0.234 ± 0.014 | 94.5825 ± 0.1674 | 3.1262 ± 0.0055 |
| L6 | 176.03 ± 7.25 | 0.283 ± 0.058 | 98.4772 ± 0.2063 | 3.2607 ± 0.0433 |
Notes: *Entrapment efficiency. **Loading efficiency.