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. 2022 Dec 11;17:6233–6255. doi: 10.2147/IJN.S384085

Table 5.

The Release Kinetic Models and the Parameters Obtained for Optimum Niosomal Formulations Containing Letrozole (L1-L3)

Release Model Zero-Order Korsmeyer–Peppas First-Order Higuchi
R2 R2 n* R2 R2
L1 0.6083 0.8476 0.5534 0.6789 0.8091
L2 0.5773 0.8775 0.3973 0.6316 0.7760
L3 0.4291 0.7056 0.3728 0.6911 0.6350

Note: *Diffusion or release exponent.