Figure 6.

By default, resting NK, γδ T, and CD8⁺ T cells are devoid of cytolytic activity. The cytolytic activity of the effector (red symbols) and resting (blue symbols) (A) NK, (B) γδ T, and (C) CD8⁺ T cells in either the presence of 5 µg/ml of the indicated antibody (solid circles) or its isotypic control (solid squares), or 500 ng/ml of peptide P26‐35 (open circles) against RAMOS (n = 7) (A), K562 (n = 5) (B), or HLA‐A*02‐expressing K562 (n = 4) (C) target cells in a 4‐h calcein release assay at different E:T ratios in 96‐well flat‐bottom plates in duplicate. Data is shown as the mean ± SEM. Normalization of the data and statistical analysis were performed as described in the Section Methods, 2.