Table 3.
Analysis for OS using the univariate and multivariate Cox proportional hazards regression model in the patient with CRC (n = 203).
| Univariate analysis |
Multivariate analysis |
|||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p Value | HR | 95% CI | p Value | |
| Age (y) | 1.277 | 0.759–2.150 | 0.357 | |||
| (≥60 vs. <60) | ||||||
| Gender | 1.534 | 0.939–2.506 | 0.087 | |||
| (Male vs. Female) | ||||||
| Location | 0.840 | 0.489–1.442 | 0.527 | |||
| (Left-side colon / rectum vs. Right-side colon) | ||||||
| TNM Stage | 2.280 | 1.447–3.593 | 0.000 | 2.306 | 1.462–3.363 | 0.000 |
| (III–IV vs. I–II) | ||||||
| MMR | 1.395 | 0.812–2.396 | 0.229 | |||
| (d-MMR vs. p-MMR) | ||||||
| HEV expression | 0.772 | 0.492–1.212 | 0.261 | 0.749 | 0.477–1.175 | 0.208 |
| (Positive vs. Negative) | ||||||
OS: overall survival; TNM: tumor-nodes-metastasis; MMR: mismatch repair; p-MMR: proficient mismatch repair; d-MMR: deficient mismatch repair; HEV: high endothelial venules; CI: confidence interval; HR: hazard ratio.