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. 2022 Dec 1;9:995103. doi: 10.3389/fmed.2022.995103

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Copyright © 2022 Xiao, Xiao and Lin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of DEGs between patients with and without renal involvement. (A) Heatmap of GSE65391, (B) principal component analysis (PCA) plot generated from DEGs in GSE49454, and (C) uniform Manifold Approximation and Projection (UMAP) showing distinct clusters of DEGs in GSE49454. Group1 stands for the patients without active renal involvement and group2 stands for patients with active renal involvement. Data points in red represent upregulated genes, and those in blue represent downregulated genes.