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. 2022 Dec 1;9:995103. doi: 10.3389/fmed.2022.995103

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Copyright © 2022 Xiao, Xiao and Lin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cluster modules extracted by MCODE and enrichment analysis of the modular genes. (A,D) Significant gene clustering modules. (B,C) GO and KEGG enrichment analysis of the first modular genes. Two cluster modules extracted by MCODE. Cluster 1 (A) had the higher cluster score (MCODE score = 13.625), followed by cluster 2 (D) (MCODE score = 8.5). Adjusted P value < 0.05 was considered significant.